ADVAIR DISKUS is for the treatment of asthma in patients 4 years and older.

ADVAIR HFA is for the treatment of asthma in patients 12 years and older.

ADVAIR should be used only if your healthcare provider decides that your asthma is not well controlled with a long-term asthma control medicine, such as an inhaled corticosteroid. ADVAIR is not for, and should not be used to treat, sudden, severe symptoms of asthma. ADVAIR won't replace a rescue inhaler.

Frequently Asked Questions

Here are some frequently asked questions about ADVAIR for asthma:

• What are the benefits of using ADVAIR for asthma?
• How does ADVAIR work?
• My symptoms seem to have gone away since I started using ADVAIR. Can I stop taking it?
• How do I take ADVAIR DISKUS?
• How do I take ADVAIR HFA?
• Do I have to carry ADVAIR with me all day long?
• Does ADVAIR replace my rescue inhaler?
• How is ADVAIR available?
• How do I store ADVAIR DISKUS?
• How do I store ADVAIR HFA (fluticasone propionate and salmeterol) Inhalation Aerosol?
• Does ADVAIR contain lactose?
• What are the possible side effects of ADVAIR?
• What is thrush? How is it treated?
• What if I am having difficulty paying for my ADVAIR DISKUS?

What are the benefits of using ADVAIR for asthma?
ADVAIR helps prevent asthma symptoms from occurring in the first place by treating the two main causes—airway constriction and inflammation. Results may vary.

Together, airway constriction and inflammation cause the airways to narrow and reduce airflow into the lungs, which may result in symptoms such as wheezing and shortness of breath. ADVAIR helps to prevent such symptoms in the first place. ADVAIR is not for, and should not be used to treat, sudden, severe symptoms of asthma. ADVAIR won't replace a rescue inhaler.

How does ADVAIR work?
ADVAIR treats the two main causes of asthma by combining two different types of medicines in one product:

• A long-acting bronchodilator. This medicine helps relax the muscles surrounding the airways
• An inhaled corticosteroid . This medicine reduces the inflammation in the airways

ADVAIR is not for, and should not be used to treat, sudden, severe symptoms of asthma. ADVAIR won't replace a rescue inhaler.

My symptoms seem to have gone away since I started using ADVAIR. Can I stop taking it?
Airway constriction and inflammation are always there whether you have symptoms or not. That's why you need to take ADVAIR as prescribed by your doctor. Do not stop using ADVAIR or other asthma medicines unless told to do so by your doctor because your symptoms might get worse. Your doctor will change your medicines as needed.

How do I take ADVAIR DISKUS?
ADVAIR DISKUS is a product that you inhale to help prevent your asthma symptoms from occurring in the first place. Take 1 inhalation of ADVAIR DISKUS twice a day, every day, as prescribed by your doctor, once in the morning and once at night, about 12 hours apart. Click here for instructions on how to use ADVAIR DISKUS.

How do I take ADVAIR HFA?
ADVAIR HFA is a product you inhale to help prevent your asthma symptoms from occurring in the first place. Take 2 inhalations of ADVAIR HFA twice a day, every day, as prescribed by your doctor, once in the morning and once at night, about 12 hours apart. Click here for instructions on how to use ADVAIR HFA.

Do I have to carry ADVAIR with me all day long?
You only need to take ADVAIR twice a day, every day, once in the morning and once at night, about 12 hours apart, as prescribed by your doctor. So there's no need to carry it with you all day. However, you should keep your rescue inhaler with you at all times for sudden asthma symptoms.

Does ADVAIR replace my rescue inhaler?
No. ADVAIR is not a rescue inhaler. You should use a rescue (fast-acting) inhaler to treat sudden asthma symptoms. The rescue inhaler helps you get control quickly when you are having asthma symptoms. Every person with asthma needs a rescue inhaler. Talk to your doctor or pharmacist for more information.

How is ADVAIR available?
ADVAIR DISKUS is available by prescription. It comes in three strengths:

• ADVAIR 100/50
• ADVAIR 250/50
• ADVAIR 500/50

If you prefer a metered-dose inhaler, you have another option, ADVAIR HFA, which is available in three strengths:

• ADVAIR HFA 45/21
• ADVAIR HFA 115/21
• ADVAIR HFA 230/21

Ask your doctor which form and dosage strength of ADVAIR may be right for you.

How do I store ADVAIR DISKUS?

• Store ADVAIR DISKUS at controlled room temperature, 20°C to
  25°C (68°F to 77°F), in a dry place away from direct heat or sunlight
• Safely discard ADVAIR DISKUS 1 month after you remove it from the foil pouch, or after the dose indicator reads "0," whichever comes first

How do I store ADVAIR HFA?

• Store ADVAIR HFA at room temperature with the mouthpiece down
• Do not puncture the canister. Do not use or store ADVAIR HFA
  near heat or an open flame. Never throw it into a fire or
  an incinerator
• Keep ADVAIR HFA and all medicines out of reach of children

Does ADVAIR contain lactose?

• ADVAIR DISKUS contains lactose. Do not use ADVAIR DISKUS if you have severe allergy to milk proteins. Ask your doctor if you are not sure.
• ADVAIR HFA does not contain lactose.

What are the possible side effects of ADVAIR?

• ADVAIR can cause serious side effects, including:
  • serious allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms of a serious allergic reaction:
    • rash
    • hives
    • swelling of the face, mouth, and tongue
    • breathing problems
  • sudden breathing problems immediately after inhaling your medicine
  • effects on heart:
    • increased blood pressure
    • a fast and irregular heartbeat
    • chest pain
  • effects on nervous system:
    • tremor
    • nervousness
  • reduced adrenal function (may result in loss of energy)
  • changes in blood (sugar, potassium, certain types of white blood cells)
  • weakened immune system and a higher chance of infections. You should avoid exposure to chickenpox and measles, and, if exposed, consult your healthcare provider without delay. Worsening of existing tuberculosis, fungal, bacterial, viral, or parasitic infections, or ocular herpes simplex may occur.
  • lower bone mineral density. This may be a problem for people who already have a higher chance of low bone density (osteoporosis).
  • eye problems including glaucoma and cataracts. You should have regular eye exams while using ADVAIR.
  • slowed growth in children. A child’s growth should be checked often.
  • ADVAIR HFA can cause throat tightness.
• Common side effects of ADVAIR DISKUS for asthma include upper respiratory tract infection, throat irritation, hoarseness and voice changes, thrush in the mouth and throat, bronchitis, cough, headache, nausea, and vomiting. In children with asthma, infections in the ear, nose, and throat are common.
• Common side effects of ADVAIR HFA for asthma include upper respiratory tract infection, headache, throat irritation, musculoskeletal pain, nausea, and vomiting.

What is thrush?
Thrush is the overgrowth of candida, a fungus, in the mouth. It can occur when the normal balance of bacteria in your mouth is altered. Talk to your doctor about how it can be treated.

What if I am having difficulty paying for my ADVAIR DISKUS?
GlaxoSmithKline offers multiple programs to help patients afford their medicine. To learn more about these programs, please go to www.GSKforYou.com.