How to Use ADVAIR HFA

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In addition to ADVAIR DISKUS, there is another option: ADVAIR HFA. ADVAIR HFA treats the two main causes of asthma symptoms—airway constriction and inflammation. ADVAIR is not for, and should not be used to treat, sudden, severe, symptoms of asthma. ADVAIR won't replace a rescue inhaler.

When your asthma is well controlled, your healthcare provider may tell you to stop taking ADVAIR. Your healthcare provider will decide if you can stop ADVAIR without loss of asthma control. Your healthcare provider may prescribe a different asthma control medicine for you, such as an inhaled corticosteroid.

ADVAIR DISKUS 100/50 (fluticasone propionate 100 mcg and salmeterol 50 mcg inhalation powder), ADVAIR HFA 45/21 (fluticasone propionate 45 mcg and salmeterol 21 mcg) Inhalation Aerosol, Continued Below, Using ADVAIR HFA, A Metered-Dose Inhaler, Live Assistance, Get your savings on ADVAIR, Learn More, See how to use ADVAIR DISKUS, Learn More, Why treat asthma with ADVAIR DISKUS?, Learn MoreADVAIR HFA is available in three strengths:
ADVAIR HFA 45/21, ADVAIR HFA 115/21, and ADVAIR HFA 230/21. Each inhaler provides either 60 or 120 metered inhalations.

Each time you use ADVAIR HFA, follow the steps below. If you have questions, ask your doctor or pharmacist.

Instructions for using your ADVAIR HFA

The parts of your ADVAIR HFA:
There are 2 main parts to your ADVAIR HFA inhaler—the metal canister that holds the medicine and the purple plastic actuator that sprays the medicine from the canister.

The canister has a counter to show how many sprays of medicine you have left. The number shows through a window in the back of the actuator. The counter starts at 124, or at 064 if you have a sample or institutional canister. The number will count down by 1 each time you spray the inhaler. The counter will stop counting at 000.

Never try to change the numbers or take the counter off the metal canister. The counter cannot be reset, and it is permanently attached to the canister.

The mouthpiece of the actuator is covered by a cap. The strap on the cap keeps it attached to the actuator.

Do not use the actuator with a canister of medicine from any other inhaler. Do not use an ADVAIR HFA canister with an actuator from any other inhaler.

Using your ADVAIR HFA

  • The inhaler should be at room temperature before you use it.
  • Take your ADVAIR HFA inhaler out of the moisture-protective pouch just before you use it for the first time. Safely throw away the foil pouch and the drying packet that comes inside the pouch.

Priming your ADVAIR HFA:
Before you use ADVAIR HFA for the first time, you must prime the inhaler so that you will get the right amount of medicine when you use it.
To prime the inhaler, take the cap off the mouthpiece and shake the inhaler well for 5 seconds. Then spray the inhaler 1 time into the air away from your face. Avoid spraying in eyes. Shake and spray the inhaler like this 3 more times to finish priming it. The counter should now read 120, or 060 if you have a sample or institutional canister.

You must prime your inhaler again if you have not used it in more than 4 weeks or if you drop it. Take the cap off the mouthpiece, shake the inhaler well for 5 seconds. Then spray it into the air away from your face. Shake and spray the inhaler like this 1 more time to finish priming it.

Instructions for taking a dose from your
ADVAIR HFA:

Read through the 7 steps below before using ADVAIR HFA. If you have any questions, ask your doctor or pharmacist.

  1. 1. Take the cap off the mouthpiece of the actuator. Look inside the mouthpiece for foreign objects, and take out any you see.

    Make sure the canister fits firmly in the actuator.

    Shake the inhaler well for 5 seconds.
  2. 2. Hold the inhaler with the mouthpiece down. Breathe out through your mouth and push as much air from your lungs as you can. Put the mouthpiece in your mouth and close your lips around it.
  3. 3. Push the top of the canister all the way down while you breathe in deeply and slowly through your mouth. Right after the spray comes out, take your finger off the canister. After you have breathed in all the way, take the inhaler out of your mouth and close your mouth.
  4. 4. Hold your breath as long as you can, up to 10 seconds, then breathe normally.
  5. 5. Wait about 30 seconds and shake the inhaler well for 5 seconds. Repeat steps 2 through 4.
  6. 6. After you finish taking this medicine, rinse your mouth with water. Spit out the water. Do not swallow it.
  7. 7. Put the cap back on the mouthpiece after every time you use the inhaler. Make sure it snaps firmly into place.

Cleaning your ADVAIR HFA:
Clean the inhaler at least 1 time each week after your evening dose. It is important to keep the canister and plastic actuator clean so the medicine will not build-up and block the spray.

  1. Take the cap off the mouthpiece. The strap on the cap will stay attached to the actuator. Do not take the canister out of the plastic actuator.
  2. Use a dry cotton swab to clean the small circular opening where the medicine sprays out of the canister. Carefully twist the swab in a circular motion to take off any medicine.
  3. Wipe the inside of the mouthpiece with a clean tissue dampened with water. Let the actuator air-dry overnight.
  4. Put the cap back on the mouthpiece after the actuator has dried.

Replacing your ADVAIR HFA:

  • When the counter reads 020, you should refill your prescription or ask your doctor if you need another prescription for ADVAIR HFA.
  • When the counter reads 000, throw the inhaler away. You should not keep using the inhaler when the counter reads 000 because you will not receive the right amount of medicine.
  • Do not use the inhaler after the expiration date, which is on the packaging it comes in.

Approved Uses for ADVAIR

ADVAIR DISKUS is for the treatment of asthma in patients 4 years and older. ADVAIR HFA is for the treatment of asthma in patients 12 years and older. ADVAIR is available by prescription only.

ADVAIR should be used only if your healthcare provider decides that your asthma is not well controlled with a long-term asthma control medicine, such as an inhaled corticosteroid.

ADVAIR is not for, and should not be used to treat, sudden, severe symptoms of asthma. ADVAIR won’t replace a rescue inhaler.

Important Safety Information About ADVAIR DISKUS® (fluticasone propionate and salmeterol inhalation powder) and ADVAIR® HFA (fluticasone propionate and salmeterol) Inhalation Aerosol

  • People with asthma who take long-acting beta2-adrenergic agonist (LABA) medicines, such as salmeterol (one of the medicines in ADVAIR), have an increased risk of death from asthma problems. It is not known whether fluticasone propionate, the other medicine in ADVAIR, reduces the risk of death from asthma problems seen with salmeterol.
    • Call your healthcare provider if breathing problems worsen over time while using ADVAIR. You may need different treatment.
    • Get emergency medical care if:
      • breathing problems worsen quickly and
      • you use your rescue inhaler medicine, but it does not relieve your breathing problems.
  • ADVAIR should be used only if your healthcare provider decides that your asthma is not well controlled with a long-term asthma control medicine, such as an inhaled corticosteroid.
  • When your asthma is well controlled, your healthcare provider may tell you to stop taking ADVAIR. Your healthcare provider will decide if you can stop ADVAIR without loss of asthma control. Your healthcare provider may prescribe a different asthma control medicine for you, such as an inhaled corticosteroid.
  • Children and adolescents with asthma who take LABA medicines may have an increased risk of hospitalization for asthma problems.
  • Do not use ADVAIR to treat sudden, severe symptoms of asthma or COPD. Always have a rescue inhaler medicine with you to treat sudden symptoms.
  • Do not use ADVAIR if you are allergic to any of the ingredients in ADVAIR. Do not use ADVAIR DISKUS if you have severe allergy to milk proteins. Ask your doctor if you are not sure.
  • Do not use ADVAIR more often than prescribed. Do not take ADVAIR with other medicines that contain a LABA for any reason. Tell your doctor about medicines you take and about all of your medical conditions.
  • ADVAIR can cause serious side effects, including:
    • serious allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms of a serious allergic reaction:
      • rash
      • hives
      • swelling of the face, mouth, and tongue
      • breathing problems
    • sudden breathing problems immediately after inhaling your medicine
    • effects on heart
      • increased blood pressure
      • a fast and irregular heartbeat
      • chest pain
    • effects on nervous system
      • tremor
      • nervousness
    • reduced adrenal function (may result in loss of energy)
    • changes in blood (sugar, potassium, certain types of white blood cells)
    • weakened immune system and a higher chance of infections. You should avoid exposure to chickenpox and measles, and, if exposed, consult your healthcare provider without delay. Worsening of existing tuberculosis, fungal, bacterial, viral, or parasitic infections, or ocular herpes simplex may occur.
    • lower bone mineral density. This may be a problem for people who already have a higher chance of low bone density (osteoporosis).
    • eye problems including glaucoma and cataracts. You should have regular eye exams while using ADVAIR.
    • slowed growth in children. A child's growth should be checked often.
    • ADVAIR HFA can cause throat tightness.
  • Common side effects of ADVAIR DISKUS for asthma include:
    • upper respiratory tract infection
    • throat irritation
    • hoarseness and voice changes
    • thrush in the mouth and throat
    • bronchitis
    • cough
    • headache
    • nausea and vomiting

    In children with asthma, infections in the ear, nose, and throat are common.

  • Common side effects of ADVAIR HFA for asthma include:
    • upper respiratory tract infection
    • throat irritation
    • hoarseness and voice changes
    • headache
    • dizziness
    • nausea and vomiting
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