How to Use ADVAIR DISKUS

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We'd like to help you use ADVAIR DISKUS correctly. Review the presentation below for using ADVAIR DISKUS, and if you have any questions, ask your healthcare provider or pharmacist.

This presentation is intended to complement the Medication Guide for ADVAIR DISKUS. For full instructions on how to use ADVAIR DISKUS, and other important information, please see the complete Prescribing Information and Medication Guide for ADVAIR DISKUS.


LEVER
Sliding the lever
(until it clicks) prepares
the dose to be inhaled
OUTER CASE
Protects the mouthpiece
when not in use
MOUTHPIECE
Where to place your
mouth to inhale the
medicine
THUMBGRIP
Where to place your
thumb while opening
and closing the DISKUS
DOSE INDICATOR
Keeps track of how many
doses you have left

Follow these instructions for using your ADVAIR DISKUS®.

  • You will breathe in (inhale) the medicine from the DISKUS®.
  • If you have any questions, ask your healthcare provider or pharmacist.

Take ADVAIR DISKUS out of the box and foil pouch. Write the "Pouch opened" and "Use by" dates on the label on top of the DISKUS®. The "Use by" date is 1 month from date of opening the pouch.

The DISKUS will be in the closed position when the pouch is opened.

The dose indicator on the top of the DISKUS tells you how many doses are left. The dose indicator number will decrease each time you use the DISKUS.

After you have used 55 doses from the DISKUS, the numbers 5 to 0 will appear in red to warn you that there are only a few doses left.

If you are using a "sample" DISKUS, the numbers 5 to 0 will appear in red after 9 doses.

Taking a dose from the DISKUS requires the
following 3 simple steps: OPEN, CLICK, INHALE.

STEP 1: OPEN

Hold the DISKUS in one hand and put the thumb of your other hand on the thumbgrip.

STEP 1: OPEN
(continued)

Push your thumb away from you as far as it will go until the mouthpiece appears and snaps into position.

STEP 2: CLICK

Hold the DISKUS in a level, flat position with the mouthpiece towards you.

STEP 2: CLICK
(continued)

Slide the lever away from you as far as it will go until it clicks. The DISKUS is now ready to use.

Every time the lever is pushed back, a dose is ready to be inhaled. This is shown by a decrease in numbers on the dose counter.

To avoid releasing or wasting doses once the DISKUS is ready:

  • Do not close the DISKUS.
  • Do not tilt the DISKUS.
  • Do not play with the lever.
  • Do not move the lever more than once.

STEP 3: INHALE

Before inhaling your dose from the DISKUS, breathe out (exhale) fully while holding the DISKUS level and away from your mouth. Remember, never breathe out into the DISKUS mouthpiece.

STEP 3: INHALE
(continued)

Put the mouthpiece to your lips. Breathe in quickly and deeply through the DISKUS. Do not breathe in through your nose.

STEP 3: INHALE
(continued)

Remove the DISKUS from your mouth. Hold your breath for about 10 seconds, or for as long as is comfortable.

STEP 3: INHALE
(continued)

Breathe out slowly.

The DISKUS delivers your dose of medicine as a very fine powder. You may or may not taste or feel the powder. Do not use an extra dose from the DISKUS if you do not feel or taste the medicine.

Rinse your mouth with water after breathing-in the medicine.

Spit the water out. Do not swallow.

4: CLOSE

Close the DISKUS when you are finished taking a dose so that the DISKUS will be ready for you to take your next dose. Put your thumb on the thumbgrip and slide the thumbgrip back towards you as far as it will go.

4: CLOSE (continued)

The DISKUS will click shut. The lever will automatically return to its original position.

The DISKUS is now ready for you to take your next scheduled dose, due in about 12 hours. (Repeat steps 1 to 4.)

  • Store ADVAIR DISKUS at room temperature between 68°F to 77°F (20°C to 25°C). Keep in a dry place away from heat and sunlight.
  • Safely discard ADVAIR DISKUS 1 month after you remove it from the foil pouch, or after the dose indicator reads "0", whichever comes first.
  • Keep ADVAIR DISKUS and all medicines out of the reach of children.
  • Never breathe into the DISKUS.
  • Never take the DISKUS apart.
  • Always ready and use the DISKUS in a level, flat position.
  • Do not use the DISKUS with a spacer device.
  • After each dose, rinse your mouth with water and spit the water out. Do not swallow.
  • Never wash the mouthpiece or any part of the DISKUS. Keep it dry.
  • Always keep the DISKUS in a dry place.
  • Never take an extra dose, even if you did not taste or feel the medicine.

Approved Uses for ADVAIR

ADVAIR DISKUS is for the treatment of asthma in patients 4 years and older. ADVAIR HFA is for the treatment of asthma in patients 12 years and older. ADVAIR is available by prescription only.

ADVAIR should be used only if your healthcare provider decides that your asthma is not well controlled with a long-term asthma control medicine, such as an inhaled corticosteroid.

ADVAIR is not for, and should not be used to treat, sudden, severe symptoms of asthma. ADVAIR won’t replace a rescue inhaler.

Important Safety Information About ADVAIR DISKUS® (fluticasone propionate and salmeterol inhalation powder) and ADVAIR® HFA (fluticasone propionate and salmeterol) Inhalation Aerosol

  • People with asthma who take long-acting beta2-adrenergic agonist (LABA) medicines, such as salmeterol (one of the medicines in ADVAIR), have an increased risk of death from asthma problems. It is not known whether fluticasone propionate, the other medicine in ADVAIR, reduces the risk of death from asthma problems seen with salmeterol.
    • Call your healthcare provider if breathing problems worsen over time while using ADVAIR. You may need different treatment.
    • Get emergency medical care if:
      • breathing problems worsen quickly and
      • you use your rescue inhaler medicine, but it does not relieve your breathing problems.
  • ADVAIR should be used only if your healthcare provider decides that your asthma is not well controlled with a long-term asthma control medicine, such as an inhaled corticosteroid.
  • When your asthma is well controlled, your healthcare provider may tell you to stop taking ADVAIR. Your healthcare provider will decide if you can stop ADVAIR without loss of asthma control. Your healthcare provider may prescribe a different asthma control medicine for you, such as an inhaled corticosteroid.
  • Children and adolescents with asthma who take LABA medicines may have an increased risk of hospitalization for asthma problems.
  • Do not use ADVAIR to treat sudden, severe symptoms of asthma or COPD. Always have a rescue inhaler medicine with you to treat sudden symptoms.
  • Do not use ADVAIR if you are allergic to any of the ingredients in ADVAIR. Do not use ADVAIR DISKUS if you have severe allergy to milk proteins. Ask your doctor if you are not sure.
  • Do not use ADVAIR more often than prescribed. Do not take ADVAIR with other medicines that contain a LABA for any reason. Tell your doctor about medicines you take and about all of your medical conditions.
  • ADVAIR can cause serious side effects, including:
    • serious allergic reactions. Call your healthcare provider or get emergency medical care if you get any of the following symptoms of a serious allergic reaction:
      • rash
      • hives
      • swelling of the face, mouth, and tongue
      • breathing problems
    • sudden breathing problems immediately after inhaling your medicine
    • effects on heart
      • increased blood pressure
      • a fast and irregular heartbeat
      • chest pain
    • effects on nervous system
      • tremor
      • nervousness
    • reduced adrenal function (may result in loss of energy)
    • changes in blood (sugar, potassium, certain types of white blood cells)
    • weakened immune system and a higher chance of infections. You should avoid exposure to chickenpox and measles, and, if exposed, consult your healthcare provider without delay. Worsening of existing tuberculosis, fungal, bacterial, viral, or parasitic infections, or ocular herpes simplex may occur.
    • lower bone mineral density. This may be a problem for people who already have a higher chance of low bone density (osteoporosis).
    • eye problems including glaucoma and cataracts. You should have regular eye exams while using ADVAIR.
    • slowed growth in children. A child's growth should be checked often.
    • ADVAIR HFA can cause throat tightness.
  • Common side effects of ADVAIR DISKUS for asthma include:
    • upper respiratory tract infection
    • throat irritation
    • hoarseness and voice changes
    • thrush in the mouth and throat
    • bronchitis
    • cough
    • headache
    • nausea and vomiting

    In children with asthma, infections in the ear, nose, and throat are common.

  • Common side effects of ADVAIR HFA for asthma include:
    • upper respiratory tract infection
    • throat irritation
    • hoarseness and voice changes
    • headache
    • dizziness
    • nausea and vomiting
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