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Important Safety Information About ADVAIR DISKUS and ADVAIR HFA 45/21, 115/21, 230/21 (fluticasone propionate and salmeterol) Inhalation Aerosol

ADVAIR contains salmeterol. In patients with asthma, medicines like salmeterol may increase the chance of asthma-related death. So ADVAIR is not for people whose asthma is well controlled on another controller medicine. Prescription ADVAIR won't replace fast-acting inhalers for sudden symptoms and should not be taken more than twice a day. ADVAIR is for people who still have symptoms on another asthma controller, or who need two controllers.

Talk to the doctor about the risks and benefits of treating asthma with ADVAIR. Do not use ADVAIR with long-acting beta₂-agonists for any reason. If taking ADVAIR, see the doctor if asthma does not improve or gets worse. Thrush in the mouth and throat may occur. Tell the doctor about any heart condition or high blood pressure. Some people may experience increased blood pressure, heart rate, or changes in heart rhythm. Inhaled corticosteroids as well as poorly controlled asthma may cause a reduction in growth rate. The long-term effect on final adult height is unknown.

ADVAIR DISKUS is for patients 4 years and older. For patients 4 to 11 years old, ADVAIR DISKUS 100/50 is for those who have asthma symptoms while on an inhaled corticosteroid.

ADVAIR HFA is for patients 12 years and older.

Complete Prescribing Information and Medication Guide for ADVAIR DISKUS^® (fluticasone propionate and salmeterol inhalation powder).

Complete Prescribing Information and Medication Guide for ADVAIR^® HFA (fluticasone propionate and salmeterol) Inhalation Aerosol.